Science and Technology Group: Difference between revisions
No edit summary |
No edit summary |
||
Line 17: | Line 17: | ||
[[Giles Yeo|Read More ...]] | [[Giles Yeo|Read More ...]] | ||
.... | == June Meeting: Giles Yeo, ''T Cells and the CAR-T Study'' == | ||
=== June 21st === | |||
T Cells and the CAR-T Study - Meeting for the 21st June[edit] | |||
Chimeric Antigen Receptor (CAR) T-cell Therapy, or CAR-T therapy for short, is a technique for creating T-cells that are genetically engineered to produce special receptors on their surface to recognize specific targeted tumor cells.These receptors are the Chimeric Antigen Receptors. They are chimeric because they incorporate genetic information from a source other than the patient. Once the T-cells are produced in sufficient quantities they can be injected into the patient. The advantage of this treatment is that the cells, because they are accepted by the patients own immune system, can remain in the body for an extended period and provide extended protection against recurrence of the disease. | |||
T-cells are a key component of our immune system that fights off infection, and indeed any 'foreign' protein that our bodies are exposed to. Cancer cells evade the attention of our immune system. By using gene editing techniques it is possible to program T cells to recognize and eliminate cancer cells that would otherwise go undetected by our bodies. This is a very promising area of work, although it is still experimental and in early stages. Pioneering work has been done at Great Ormond Street Hospital, and we are delighted to welcome Prof Paul Veys to speak to the meeting of the Reform Club Science Group. | |||
[[Paul Veys|Read More ...]] | |||
= 2017 Programme = | = 2017 Programme = |
Revision as of 04:05, 20 April 2017
May Meeting: Giles Yeo, Are your genes to blame if your jeans don't fit?
May 16th, Strangers Room
Obesity may well be the world’s largest public health problem.
The recent rapid increase in obesity must be down to changes in our lifestyle and in the types of food we eat. It is clear that our environment has changed a lot over the past fifty years. People take much less exercise and consume far more calories than ever before.
Although we are all exposed to these changes, only some of us are obese.
Our response to this changed environment depenfileds on our genetic make-up. Twin studies estimate that 40% to 70% of the variability of our weight may be due to genetic factors.
Once we realize this, we can use genetics as a tool to understand human obesity. The focus of Dr Yeo’s group is on the molecular mechanisms underlying obesity. It has made major advances in understanding the biology of appetite control. It appears that some of us simply feel hungrier all the time and, as a result, eat more.
Dr Yeo will challenge the prevailing view that obese people are bad, lazy and lacking in moral fibre. He argues rather that they are fighting their biology, at least in most cases. Society will have to accept this before it can come up with strategies to tackle the problem successfully.
June Meeting: Giles Yeo, T Cells and the CAR-T Study
June 21st
T Cells and the CAR-T Study - Meeting for the 21st June[edit] Chimeric Antigen Receptor (CAR) T-cell Therapy, or CAR-T therapy for short, is a technique for creating T-cells that are genetically engineered to produce special receptors on their surface to recognize specific targeted tumor cells.These receptors are the Chimeric Antigen Receptors. They are chimeric because they incorporate genetic information from a source other than the patient. Once the T-cells are produced in sufficient quantities they can be injected into the patient. The advantage of this treatment is that the cells, because they are accepted by the patients own immune system, can remain in the body for an extended period and provide extended protection against recurrence of the disease.
T-cells are a key component of our immune system that fights off infection, and indeed any 'foreign' protein that our bodies are exposed to. Cancer cells evade the attention of our immune system. By using gene editing techniques it is possible to program T cells to recognize and eliminate cancer cells that would otherwise go undetected by our bodies. This is a very promising area of work, although it is still experimental and in early stages. Pioneering work has been done at Great Ormond Street Hospital, and we are delighted to welcome Prof Paul Veys to speak to the meeting of the Reform Club Science Group.
2017 Programme
Dates for 2017 are as follows (all meeting are on Wednesdays, usually the 3rd one of each month):
Month | Day of Month | Speaker | Title |
---|---|---|---|
February | 15th | Prof Martyn Thomas | Cybersecurity |
March | 15th | Prof Anil Seth | Machine Consciousness |
April | 19th | Prof Peter Wilson | Anti-Microbial Resistance. |
May | 16th, | Dr Giles Yeo | Are your genes to blame if your jeans don't fit? |
June | 21st | Prof Paul Veys | CAR-T Study, Anthony Nolan. |
September | 20th | Dr Paolo Tasca | Bitcoins and the Blockchain |
October | 18th | Prof J A Madrigal | Stem cell therapies. |
November | 15th | Dr Uday Phadke | Innovation |
2018 Programme
Dates for 2018 are as follows (usually 3rd Wed of each month):
Month | Day of Month | Speaker | Title |
---|---|---|---|
February | 21st | ||
March | 14th | ||
April | 25th | ||
May | 23rd | ||
June | 20th | ||
September | 11th | ||
October | 24th | ||
November | 28th |